Born in 1469

Feb 20 Thomas Cajetan an Italian philosopher, theologian, cardinal and the Master of the Order of Preachers 1508-18. He was a leading theologian of his day who is now best known as the spokesman for Catholic opposition to the teachings of Martin Luther and the Protestant Reformation while he was the Pope's Legate in Wittenberg, and perhaps also among Catholics for his extensive commentary on the Summa Theologica of Thomas Aquinas
Mar 20 Cecily of York an English Princess and the third, but eventual second surviving, daughter of Edward IV, King of England and his queen consort, née Lady Elizabeth Woodville, daughter of Richard Woodville, 1st Earl Rivers and Jacquetta of Luxembourg.
Apr 15 Guru Nanak the founder of Sikhism and the first of the Sikh Gurus. His birth is celebrated world-wide on Kartik Puranmashi, the full-moon day which falls on different dates each year in the month of Katak, October–November
May 3 Niccolò Machiavelli an Italian historian, politician, diplomat, philosopher, humanist, and writer based in Florence during the Renaissance. He was for many years an official in the Florentine Republic, with responsibilities in diplomatic and military affairs. He was a founder of modern political science, and more specifically political ethics. He also wrote comedies, carnival songs, and poetry. His personal correspondence is renowned in the Italian language. He was Secretary to the Second Chancery of the Republic of Florence from 1498 to 1512, when the Medici were out of power. He wrote his masterpiece, The Prince, after the Medici had recovered power and he no longer held a position of responsibility in Florence
May 31 Manuel I of Portugal the son of Infante Ferdinand, Duke of Viseu, , by his wife, Infanta Beatrice of Portugal. His name is associated with a period of Portuguese civilization distinguished by significant achievements both in political affairs and the arts. In spite of its small size and population in comparison to the great land powers of Europe, it was able to acquire an overseas empire of vast proportions and with a global dimension, for the first time in history, during Manuel's reign
Jun 20 Gian Galeazzo Sforza the sixth Duke of Milan.
Aug 26 Ferdinand II of Naples King of Naples from 1495 to 1496. He was the son and successor of Alphonso II, and heir of the Brienne claim to kingdom of Jerusalem
Oct 19 John Fisher an English Catholic Cardinal-Priest, Bishop, and theologian. He was a man of learning, associated with the intellectuals and political leaders of his day, and eventually became Chancellor of the University of Cambridge