Born in 1475

Jan 9 Crinitus a Florentine humanist scholar.
Jan 29 Giuliano Bugiardini an Italian painter of the late-Renaissance period known as Mannerism, born and mainly active in Florence.
Feb 25 Edward Plantagenet 17th Earl of Warwick the son of George Plantagenet, 1st Duke of Clarence, and a potential claimant to the English throne during the reigns of both Richard III and his successor, Henry VII. He was also a younger brother of Margaret Pole, 8th Countess of Salisbury
Mar 6 Michelangelo an Italian sculptor, painter, architect, poet, and engineer of the High Renaissance who exerted an unparalleled influence on the development of Western art. Despite making few forays beyond the arts, his versatility in the disciplines he took up was of such a high order that he is often considered a contender for the title of the archetypal Renaissance man, along with his fellow Italian Leonardo da Vinci
Jun 29 Beatrice d'Este the wife of the Milanese ruler Ludovico Sforza. She was one of the most beautiful and accomplished princesses of the Italian Renaissance. A member of the Este family, she was the younger daughter of Ercole I d'Este and the sister of Isabella d'Este and Alfonso d'Este. Along with her sister, Beatrice was noted for her excellent taste in fashion and for having invented new clothing styles
Sep 6 Sebastiano Serlio an Italian Mannerist architect, who was part of the Italian team building the Palace of Fontainebleau. Serlio helped canonize the classical orders of architecture in his influential treatise variously known as I sette libri dell'architettura or Tutte l'opere d'architettura et prospetiva
Sep 13 Cesare Borgia an Italian condottiero, nobleman, politician, and cardinal. He was the illegitimate son of Pope Alexander VI and his long-term mistress Vannozza dei Cattanei. He was the brother of Lucrezia Borgia; Giovanni Borgia , Duke of Gandia; and Gioffre Borgia , Prince of Squillace. He was half-brother to Don Pedro Luis de Borja and Girolama de Borja, children of unknown mothers
Oct 20 Giovanni di Bernardo Rucellai an Italian humanist, poet, dramatist and man of letters in Renaissance Florence, in Tuscany, Italy. A member of a wealthy family of wool merchants and one of the richest men in Florence, he was cousin to Pope Leo X and linked by marriage to the powerful Strozzi and de' Medici families. He was born in Florence, and died in Rome. He was the son of Bernardo Rucellai and grandson of Giovanni di Paolo Rucellai. He is now remembered mostly for his poem Le Api, "The Bees"
Dec 11 Pope Leo X Pope from 9 March 1513 to his death in 1521. The second son of Lorenzo the Magnificent, ruler of the Florentine Republic, he was elevated to the cardinalate in 1489
Dec 24 Thomas Murner a German satirist, poet and translator.