Born in 1479

Mar 12 Giuliano de' Medici Duke of Nemours an Italian nobleman, the third son of Lorenzo the Magnificent.
Mar 25 Vasili III of Russia the Grand Prince of Moscow from 1505 to 1533. He was the son of Ivan III Vasiliyevich and Sophia Paleologue and was christened with the name Gavriil. He had three brothers; Yuri, born in 1480, Simeon, born in 1487 and Andrei, born in 1490, as well as five sisters: Elena , Feodosiya , another Elena , another Feodosiya and Eudoxia
Apr 25 Sylvester of the River Obnora recognized as a saint. Sylvester was inspired by the teachings of Sergius of Radonez. He was trained at Trinity Monastery. Sylvester then went as a hermit to live along the banks of the River Obnora, living on either herbs or tree bark and roots. He nearly died but is said to have received sustenance from an angel that saved him. Later others joined him and he established a monastery
May 3 Henry V Duke of Mecklenburg the reigning Duke of Mecklenburg in the region Mecklenburg-Schwerin, the son of Duke Magnus II and Sophie of Pomerania-Stettin.
May 5 Guru Amar Das the third of the Ten Gurus of Sikhism and was given the title of Sikh Guru on 26 March 1552. He died at an age of 95
May 12 Pompeo Colonna an Italian Cardinal, politician and condottiero.
Jun 14 Giglio Gregorio Giraldi an Italian scholar and poet.
Jun 15 Lisa del Giocondo a member of the Gherardini family of Florence and Tuscany in Italy. Her name was given to Mona Lisa, her portrait commissioned by her husband and painted by Leonardo da Vinci during the Italian Renaissance
Aug 14 Catherine of York the ninth child and sixth daughter of King Edward IV by his wife Elizabeth Woodville. From birth to death, she was daughter to Edward IV, sister to Edward V, niece to Richard III, sister-in-law to Henry VII and aunt to Henry VIII
Nov 6 Joanna of Castile queen of Castile from 1504 and of Aragon from 1516. From the union of these two crowns modern Spain evolved. Joanna married Philip the Handsome, who was crowned King of Castile in 1506, initiating the rule of the Habsburgs in Spain. After Philip's death that same year, Joanna was deemed mentally ill and was confined to a nunnery for the rest of her life. Though she remained the legal queen of Castile throughout this time, her father, Ferdinand II of Aragon, was regent until his death, when she inherited his kingdom as well. From 1517, her son, Charles, ruled as king, while she nominally remained co-monarch
Dec 5 Ayşe Hafsa Sultan the first "Valide Sultan" of the Ottoman Empire, the daughter of Abd'ûl-Muin, wife of Selim I and mother of Suleiman the Magnificent. During the period between her son's enthronement in 1520 and her death in 1534, she was one of the most influential persons in the Empire, as her son's de facto co-regent during these fourteen years, coming second only to the sovereign, which is a point remarked also by the ambassadors of European powers at the Ottoman court