Born in 1480

Jan 10 Margaret of Austria Duchess of Savoy Governor of the Habsburg Netherlands from 1507 to 1515 and again from 1519 to 1530.
Feb 13 Girolamo Aleandro an Italian cardinal, and the first cardinal appointed in pectore.
Apr 10 Philibert II Duke of Savoy the Duke of Savoy from 1497 until his death.
Apr 18 Lucrezia Borgia the daughter of Pope Alexander VI and Vannozza dei Cattanei. Her brothers included Cesare Borgia, Giovanni Borgia, and Gioffre Borgia
Jun 1 Tiedemann Giese a member of the patrician Giese family of Danzig. His father was Albrecht Giese and his brother, the Hanseatic League merchant Georg Giese. Another relative was Albrecht Giese. Tiedemann became Bishop of Culm first canon, later Prince-Bishop of Warmia
Oct 1 Saint Cajetan an Italian Catholic priest and religious reformer, who helped found the Theatines. He is recognised as a saint in the Catholic Church, and his feast day is August 7
Oct 20 Vannoccio Biringuccio an Italian metallurgist. He is best known for his manual on metalworking, De la pirotechnia, published posthumously in 1540. Biringuccio is considered by some as the father of the foundry industry as De la pirotechnia is the first printed account of proper foundry practice. It also gives details of mining practice, the extraction and refining of numerous metals, alloys such as brass, and compounds used in foundries and explosives. It preceded the printing of De re metallica by Georgius Agricola by 14 years
Nov 10 Bridget of York an English princess, the tenth child and seventh daughter of Edward IV of England and Queen Elizabeth Woodville.