Born in 1483

Jan 12 Henry III of Nassau-Breda a count of the House of Nassau.
Feb 14 Ridolfo Ghirlandaio an Italian Renaissance painter active mainly in Florence. Ridolfo Ghirlandaio was the son of the Italian Renaissance painter Domenico Ghirlandaio
Feb 14 Babur a conqueror from Central Asia who, following a series of setbacks, finally succeeded in laying the basis for the Mughal dynasty in the Indian Subcontinent and became the first Mughal emperor. He was a direct descendant of Timur, from the Barlas clan, through his father, and also a descendant of Genghis Khan through his mother. Culturally, he was greatly influenced by the Persian culture and this affected both his own actions and those of his successors, giving rise to a significant expansion of the Persianate ethos in the Indian subcontinent
Mar 6 Francesco Guicciardini an Italian historian and statesman. A friend and critic of Niccolò Machiavelli, he is considered one of the major political writers of the Italian Renaissance. In his masterpiece, The History of Italy, Guicciardini paved the way for a new style in historiography, with his use of government sources to support arguments and the realistic analysis of the people and events of his time
Mar 28 Raphael an Italian painter and architect of the High Renaissance. His work is admired for its clarity of form, ease of composition, and visual achievement of the Neoplatonic ideal of human grandeur. Together with Michelangelo and Leonardo da Vinci, he forms the traditional trinity of great masters of that period
Apr 19 Paolo Giovio an Italian physician, historian, biographer, and prelate.
Oct 16 Gasparo Contarini an Italian diplomat, cardinal and Bishop of Belluno. He was one of the first proponents of the dialogue with Protestants, after the Reformation
Nov 10 Martin Luther a German friar, Catholic priest, professor of theology and seminal figure of the 16th-century movement in Christianity known later as the Protestant Reformation. Initially an Augustinian friar, Luther came to reject several teachings and practices of the Roman Catholic Church. He strongly disputed the claim that freedom from God's punishment for sin could be purchased with money. He confronted indulgence salesman Johann Tetzel, a Dominican friar, with his Ninety-Five Theses in 1517. His refusal to retract all of his writings at the demand of Pope Leo X in 1520 and the Holy Roman Emperor Charles V at the Diet of Worms in 1521 resulted in his excommunication by the Pope and condemnation as an outlaw by the Emperor
Dec 3 Nicolaus von Amsdorf a German theologian and Protestant reformer.