Born in 1487

Feb 2 John Zápolya King of Hungary from 1526 to 1540. His rule was disputed by Archduke Ferdinand I, who also claimed the title King of Hungary. He was Voivode of Transylvania before his coronation
Feb 8 Ulrich Duke of Württemberg succeeded his kinsman Eberhard II as Duke of Württemberg in 1498. He was declared of age in 1503
Apr 10 William I Count of Nassau-Dillenburg a count of Nassau-Dillenburg from the House of Nassau. He was not wealthy; his nickname the Rich refers to him having many children
Jul 5 Johann Gramann a German pastor, theologian, teacher, humanist, reformer, and Lutheran leader.
Jul 17 Ismail I Shah of Iran and the founder of the Safavid dynasty which survived until 1736. Isma'il started his campaign in Iranian Azerbaijan in 1500 as the leader of the Safaviyya, a Twelver Shia militant religious order, and unified all of Iran by 1509. Born in Ardabil in Northwestern Iran, he reigned as Shah Ismail I of Iran from 1501 to 1524
Aug 27 Anna of Brandenburg a German noblewoman.
Sep 10 Pope Julius III Pope from 7 February 1550 to his death in 1555.
Nov 14 John III of Pernstein High Treasurer of Moravia from 1506 and 1516 and Landeshauptmann of Moravia from 1515 to 1519 and from 1526 to 1528 and Governor of Moravia from 1530 to 1532. From 1537 to 1548, he was Count of Kladsko and pledge lord of the County of Kladsko