Born in 1491

May 10 Suzanne Duchess of Bourbon suo jure Duchess of Bourbon and Auvergne from 1503 to her death. Her husband was Charles de Bourbon
Jun 28 Henry VIII of England King of England from 21 April 1509 until his death. He was Lord, and later assumed the Kingship, of Ireland, and continued the nominal claim by English monarchs to the Kingdom of France. Henry was the second monarch of the Tudor dynasty, succeeding his father, Henry VII
Aug 3 Maria of Jülich-Berg born in Jülich, the daughter of Wilhelm IV, Duke of Jülich-Berg and Sibylle of Brandenburg.
Oct 23 Ignatius of Loyola a Spanish knight from a local Basque noble family, hermit, priest since 1537, and theologian, who founded the Society of Jesus and, on 19 April 1541, became its first Superior General. Ignatius emerged as a religious leader during the Counter-Reformation. Loyola's devotion to the Catholic Church was characterized by absolute obedience to the Pope
Oct 26 Zhengde Emperor the Ming dynasty Emperor of China between 1505–1521. Born Zhu Houzhao, he was the Hongzhi Emperor's eldest son. His era name means "Right virtue" or "Rectification of virtue"
Nov 8 Teofilo Folengo one of the principal Italian macaronic poets.
Nov 11 Martin Bucer a Protestant reformer based in Strasbourg who influenced Lutheran, Calvinist, and Anglican doctrines and practices. Bucer was originally a member of the Dominican Order, but after meeting and being influenced by Martin Luther in 1518 he arranged for his monastic vows to be annulled. He then began to work for the Reformation, with the support of Franz von Sickingen
Dec 31 Jacques Cartier now Canada for France. Jacques Cartier was the first European to describe and map the Gulf of Saint Lawrence and the shores of the Saint Lawrence River, which he named "The Country of Canadas", after the Iroquois names for the two big settlements he saw at Stadacona and at Hochelaga