Born in 1510

Mar 25 Guillaume Postel a French linguist, astronomer, Cabbalist, diplomat, professor, and religious universalist.
Mar 30 Antonio de Cabezón a Spanish Renaissance composer and organist. Blind from childhood, he quickly rose to prominence as performer and was eventually employed by the royal family. He was among the most important composers of his time and the first major Iberian keyboard composer
Apr 1 Alexander II of Imereti a king of Georgia in 1478 and of Imereti from 1483 to 1510.
Jun 22 Alessandro de' Medici Duke of Florence ruler of Florence from 1530 until 1537. Though illegitimate, he was the last member of the "senior" branch of the Medici to rule Florence and the first to be a hereditary duke
Aug 11 Margaret Paleologa an Italian ruler; Marchioness of Montferrat in her own right. She also married into the Gonzaga family, rulers of Mantua, making her Duchess of Mantua by her marriage to Federico II, Duke of Mantua. Margaret was the regent of Mantua as the guardian of her two sons from 1540 until 1556 in companionship with her brother-in-law
Oct 6 John Caius an English physician, and second founder of the present Gonville and Caius College, Cambridge.
Oct 6 Rowland Taylor an English Protestant martyr during the Marian Persecutions.
Oct 25 Renée of France the younger surviving child of Louis XII of France and Anne of Brittany. She was the Duchess of Ferrara due to her marriage to Ercole II d'Este, grandson of Pope Alexander In her later life she became an important supporter of the Protestant reformation and ally of John Calvin
Oct 28 Francis Borgia 4th Duke of Gandía a Grandee of Spain, a Spanish Jesuit, and third Superior General of the Society of Jesus. He was canonized on 20 June 1670 by Pope Clement X
Dec 28 Nicholas Bacon (Lord Keeper) an English politician during the reign of Queen Elizabeth I of England, notable as Lord Keeper of the Great Seal. He was the father of the philosopher and statesman Sir Francis Bacon