Died in 1510

Feb 28 Juan de la Cosa a Spanish navigator and cartographer, known for designing the earliest European world map that incorporated the territories of the Americas that were discovered in the 15th century. De la Cosa played an important role in the first and second voyage of Christopher Columbus to the West Indies, since he was the owner and captain of the Santa María
Mar 1 Francisco de Almeida a Portuguese nobleman, soldier and explorer. He distinguished himself as a counsellor to King John II of Portugal and later in the wars against the Moors and in the conquest of Granada in 1492. In 1503 he was appointed as the first governor and viceroy of the Portuguese State of India. Almeida is credited with establishing Portuguese hegemony in the Indian Ocean, with his victory at the naval Battle of Diu in 1509. Before Almeida could return to Portugal, he lost his life in 1510. His son Lourenço de Almeida too was killed in the Battle of Chaul in 1508
Mar 10 Johann Geiler von Kaisersberg a Swiss-born priest, considered one of the greatest of the popular preachers of the 15th century.
Mar 12 Mihnea cel Rău Voivode of Wallachia from 1508 to 1509, having replaced his first cousin Radu cel Mare. During his reign, he ruled alongside his son Mircea III Dracul in the year 1509. Unpopular among the boyars, he was overthrown with Ottoman assistance, prompting him to take refuge in Transylvania - where he was to be murdered in front of the Sibiu Cathedral, being buried inside the church
May 17 Sandro Botticelli an Italian painter of the Early Renaissance. He belonged to the Florentine School under the patronage of Lorenzo de' Medici, a movement that Giorgio Vasari would characterize less than a hundred years later as a "golden age", a thought, suitably enough, he expressed at the head of his Vita of Botticelli. Botticelli's posthumous reputation suffered until the late 19th century; since then his work has been seen to represent the linear grace of Early Renaissance painting. Among his best known works are The Birth of Venus and Primavera
May 25 Georges d'Amboise a French Roman Catholic cardinal and minister of state. He belonged to the house of Amboise, a noble family possessed of considerable influence: of his nine brothers, four were bishops. His father, Pierre d'Amboise, seigneur de Chaumont, was chamberlain to Charles VII and Louis XI and ambassador at Rome. Georges' eldest brother, Charles, was governor of the Île-de-France, Champagne and Burgundy, and councillor of Louis XI
Jul 10 Catherine Cornaro Queen of Cyprus from 26 August 1474 to 26 February 1489 and declared a "Daughter of Saint Mark" in order that Venice could claim control of Cyprus after the death of her husband, James II.
Jul 27 Giovanni Sforza an Italian condottiero, lord of Pesaro and Gradara from 1483 until his death. He is best known as the first husband of Lucrezia Borgia. Their marriage was annulled on claims of his impotence in March 1497
Aug 17 Edmund Dudley an English administrator and a financial agent of King Henry VII. He served as Speaker of the House of Commons and President of the King's Council. After the accession of Henry VIII, he was imprisoned in the Tower of London and executed the next year on a treason charge. While waiting for his execution he wrote The Tree of Commonwealth
Aug 23 Ulrich Gering came from Beromünster in the diocese of Constance. He was one of three partners to establish the first printing press in France
Sep 15 Catherine of Genoa an Italian Roman Catholic saint and mystic, admired for her work among the sick and the poor and remembered because of various writings describing both these actions and her mystical experiences. She was a member of the noble Fieschi family, and spent most of her life and her means serving the sick, especially during the plague which ravaged Genoa in 1497 and 1501. She died in that city in 1510
Sep 18 Ursula of Brandenburg a German noblewoman.
Nov 11 Bohuslav Hasištejnský z Lobkovic a nobleman, writer and humanist of old Bohemian family of Lobkovic.
Dec 2 Muhammad Shaybani an Uzbek leader who consolidated various Uzbek tribes and laid the foundations for their ascendance in Transoxiana and the establishment of the Khanate of Bukhara. He was a descendant of Shiban , the fifth son of Jochi,Genghis Khan's eldest son
Dec 14 Frederick of Saxony (Teutonic Knight) the 36th Grand Master of the Teutonic Knights, serving from 1498-1510. He was the third son of Albert, Duke of Saxony, and Sidonie of Poděbrady, daughter of George of Podebrady
Dec 31 Bianca Maria Sforza Holy Roman Empress as the second wife of Maximilian I, Holy Roman Emperor. She was the eldest legitimate daughter of Galeazzo Maria Sforza, Duke of Milan, by his second wife, Bona of Savoy