Born in 1519

Jan 1 Gómez Pérez Dasmariñas a Spanish politician, diplomat, military officer and colonial official. He was the seventh governor-general of the Philippines from May or June 1, 1590 to October 25, 1593. The city of Dasmariñas, located 24 km south of Manila, was named after him. Dasmariñas was a member of the Order of Santiago
Jan 18 Isabella Jagiellon Queen consort of the "Eastern Hungarian Kingdom" as the wife of John Zápolya.
Feb 5 René of Chalon a Prince of Orange and stadtholder of Holland, Zeeland, Utrecht and Gelre.
Feb 15 Pedro Menéndez de Avilés a Spanish admiral and explorer from the region of Asturias, Spain, remembered for planning the first regular trans-oceanic convoys and for founding Augustine, Florida in 1565. This was the first successful Spanish settlement in La Florida and the most significant city in the region for nearly three hundred years. Augustine is the oldest continuously inhabited European-established settlement in the continental United States. Menéndez subsequently became the first governor of Florida
Feb 16 Gaspard II de Coligny a French nobleman and admiral, best remembered as a disciplined Huguenot leader in the French Wars of Religion.
Feb 17 Francis Duke of Guise a French soldier and politician.
Mar 17 Thoinot Arbeau the anagrammatic pen name of French cleric Jehan Tabourot. Tabourot is most famous for his Orchésographie, a study of late sixteenth-century French Renaissance social dance. He was born in Dijon and died in Langres
Mar 22 Catherine Willoughby 12th Baroness Willoughby de Eresby an English noblewoman living at the royal courts of King Henry VIII, King Edward VI and later, Queen Elizabeth She was the fourth wife of Charles Brandon, 1st Duke of Suffolk, who acted as her legal guardian during his third marriage to Mary Tudor, the younger sister of Henry VIII. Her second husband was Richard Bertie, a member of her household. Following Charles Brandon's death in 1545, it was rumoured that King Henry had considered marrying Catherine as his seventh wife, while he was still married to his sixth wife, Catherine Parr, who was Catherine's close friend
Mar 31 Henry II of France a monarch of the House of Valois who ruled as King of France from 31 March 1547 until his death in 1559. The second son of Francis I, he became Dauphin of France upon the death of his elder brother Francis III, Duke of Brittany, in 1536
Apr 13 Catherine de' Medici an Italian noblewoman who was Queen of France from 1547 until 1559, as the wife of King Henry As the mother of three sons who became kings of France during her lifetime she had extensive, if at times varying, influence in the political life of France. For a time she ruled France as its regent
May 27 Girolamo Mei an Italian historian and humanist, famous in music history for providing the intellectual impetus to the Florentine Camerata, which attempted to revive ancient Greek music drama. He was born Florence, and died in Rome
Jun 12 Cosimo I de' Medici Grand Duke of Tuscany the second Duke of Florence from 1537 until 1569, when he became the first Grand Duke of Tuscany.
Jun 15 Henry FitzRoy 1st Duke of Richmond and Somerset the son of King Henry VIII of England and his mistress Elizabeth Blount, and the only illegitimate offspring whom Henry acknowledged. He was the younger half-brother of Mary I, future Queen of England , as well as the older half-brother of the future Elizabeth I and Edward Through his mother he was the elder brother of Elizabeth Tailboys, 4th Baroness Tailboys of Kyme, George Tailboys, 2nd Baron Tailboys of Kyme and Robert Tailboys, 3rd Baron Tailboys of Kyme
Jun 23 Johannes Goropius Becanus a Dutch physician, linguist, and humanist.
Jun 24 Theodore Beza a French Protestant Christian theologian and scholar who played an important role in the Reformation. A member of the monarchomaque movement who opposed absolute monarchy, he was a disciple of John Calvin and lived most of his life in Switzerland
Jul 20 Pope Innocent IX Pope from 29 October to 30 December 1591. Prior to his short papacy, he had been a Canon Lawyer, diplomat, and chief administrator during the reign of Pope Gregory XIV
Sep 23 Francis Count of Enghien a French prince of the blood. He was the son of Charles de Bourbon, Duke of Vendôme
Nov 22 Johannes Crato von Krafftheim a German humanist and court physician to three Holy Roman emperors.