Died in 1519

Jan 12 Maximilian I Holy Roman Emperor King of the Romans from 1486 and Holy Roman Emperor from 1508 until his death, though he was never in fact crowned by the Pope, the journey to Rome always being too risky. He had ruled jointly with his father for the last ten years of his father's reign, from 1483. He expanded the influence of the House of Habsburg through war and his marriage in 1477 to Mary of Burgundy, the heiress to the Duchy of Burgundy, but he also lost the Austrian territories in today's Switzerland to the Swiss Confederacy
Mar 29 Francesco II Gonzaga Marquess of Mantua the ruler of the Italian city of Mantua from 1484 until his death.
Apr 28 Madeleine de La Tour d'Auvergne a younger daughter of Jean III de La Tour , Count of Auvergne and Lauraguais, and Jeanne de Bourbon-Vendôme. She was a penultimate representative of the senior branch of the house de La Tour d'Auvergne. Madeleine is perhaps best known for being the mother of Catherine de' Medici, the future Queen of France
May 2 Leonardo da Vinci an Italian polymath, painter, sculptor, architect, musician, mathematician, engineer, inventor, anatomist, geologist, cartographer, botanist, and writer. He is widely considered to be one of the greatest painters of all time and perhaps the most diversely talented person ever to have lived. His genius, perhaps more than that of any other figure, epitomized the Renaissance humanist ideal. Leonardo has often been described as the archetype of the Renaissance Man, a man of "unquenchable curiosity" and "feverishly inventive imagination". According to art historian Helen Gardner, the scope and depth of his interests were without precedent and "his mind and personality seem to us superhuman, the man himself mysterious and remote". Marco Rosci states that while there is much speculation about Leonardo, his vision of the world is essentially logical rather than mysterious, and that the empirical methods he employed were unusual for his time
May 4 Lorenzo de' Medici Duke of Urbino the ruler of Florence from 1513 to his death in 1519. He was also Duke of Urbino from 1516 to 1519. His illegitimate son, Alessandro de' Medici, became the first Duke of Florence
Jun 24 Lucrezia Borgia the daughter of Pope Alexander VI and Vannozza dei Cattanei. Her brothers included Cesare Borgia, Giovanni Borgia, and Gioffre Borgia
Aug 11 Johann Tetzel a Roman Catholic German Dominican friar and preacher. In addition, he was a Grand Inquisitor of Heresy to Poland, and later became the Grand Commissioner for indulgences in Germany. Tetzel was reputedly known for granting indulgences in exchange for money, which allow a remission of temporal punishment due to sin, the guilt of which has been forgiven, a position heavily challenged by Martin Luther
Aug 23 Philibert Berthelier (Geneva patriot) a Swiss patriot, an uncompromising enemy of the Duke of Savoy in his ambition to lord it over Geneva.
Sep 8 Hōjō Sōun the first head of the Late Hōjō clan, one of the major powers in Japan's Sengoku period. Born Ise Moritoki, he was originally known as Ise Shinkurō, a samurai of Taira lineage from a reputable family of Shogunate officials. Although he only belonged to a side branch of the main, more prestigious Ise family, he fought his way up, gaining territory and changing his name in imitation of the illustrious Hōjō
Sep 10 John Colet an English churchman and educational pioneer.
Nov 30 Michael Wolgemut a German painter and printmaker, who was born and ran a workshop in Nuremberg. He taught Albrecht Dürer