Born in 1521

Mar 21 Maurice Elector of Saxony Duke and later Elector of Saxony. His clever manipulation of alliances and disputes gained the Albertine branch of the Wettin dynasty extensive lands and the electoral dignity
Apr 18 François de Coligny d'Andelot one of the leaders of French Protestantism during the French Wars of Religion. The son of Gaspard I de Coligny, he was the younger brother of Odet, cardinal de Châtillon and Gaspard de Coligny the admiral
May 8 Peter Canisius an important Jesuit Catholic priest who supported the Catholic faith during the Protestant Reformation in Germany, Austria, Bohemia, Moravia, and Switzerland. The restoration of the Catholic Church in Germany after the Protestant Reformation is largely attributed to the work there of the Society of Jesus, which he led. He is venerated in the Catholic Church as a saint and as a Doctor of the Church
May 10 John Ernest Duke of Saxe-Coburg a Duke of Saxe-Coburg.
Jun 18 Maria of Portugal Duchess of Viseu a Portuguese infanta daughter of King Manuel I and his wife Eleanor of Austria.
Jun 21 John II Duke of Schleswig-Holstein-Haderslev the only Duke of Schleswig-Holstein-Haderslev. The predicate the Elder is sometimes used to distinguish him from his nephew John the Younger, who held Sønderborg from 1564 as a partitioned-off duke. As a co-ruler in the duchies of Holstein and of Schleswig John the Elder is numbered Duke John II, continuing counting John of Denmark as Duke John I of Holstein and of Schleswig
Jul 8 Jorge Álvares credited as the first European explorer to have reached China and Hong Kong by sea.
Aug 4 Pope Urban VII Pope from 15 to 27 September 1590. His thirteen-day papacy was the shortest in history
Dec 1 Takeda Shingen a pre-eminent daimyo in feudal Japan with exceptional military prestige in the late stage of the Sengoku period.