Died in 1531

Feb 16 Johannes Stöffler a German mathematician, astronomer, astrologer, priest, maker of astronomical instruments and professor at the University of Tübingen.
Mar 6 Pedro Arias Dávila a Spanish colonial administrator. He led the first great Spanish expedition in the New World. For the date of birth, refer to Aram, Bethany. Leyenda negra y leyendas doradas en la conquista de América: Pedrarias y Balboa. Madrid: Marcial Pons historia, 2008
May 17 Konrad Wimpina a German Roman Catholic theologian and humanist of the early Reformation period. He was a quiet and stubborn conservative, considered quiet but somewhat narrow. In theology he was a pupil of Martin Polich of Mellerstadt and a Thomist
May 19 Jan Łaski (1456–1531) a Polish nobleman, Grand Chancellor of the Crown , diplomat, from 1490 secretary to Poland's King Casimir IV Jagiellon and from 1508 coadjutor to the Archbishop of Lwów.
Jul 7 Tilman Riemenschneider a German sculptor and woodcarver active in Würzburg from 1483. He was one of the most prolific and versatile sculptors of the transition period between late Gothic and Renaissance, a master in stone and limewood
Jul 17 Hosokawa Takakuni Japanese commander
Sep 7 Gregor Haloander a German legal scholar. He authored a recension of the Digest of Roman law
Sep 22 Louise of Savoy a French noblewoman, Duchess regnant of Auvergne and Bourbon, Duchess of Nemours, the mother of King Francis I of France. She was politically active and served as the Regent of France in 1515, in 1525–1526 and in 1529
Oct 11 Huldrych Zwingli a leader of the Reformation in Switzerland. Born during a time of emerging Swiss patriotism and increasing criticism of the Swiss mercenary system, he attended the University of Vienna and the University of Basel, a scholarly centre of Renaissance humanism. He continued his studies while he served as a pastor in Glarus and later in Einsiedeln, where he was influenced by the writings of Erasmus
Oct 19 Fadrique Álvarez de Toledo 2nd Duke of Alba a Spanish nobleman, military leader and politician.
Nov 24 Johannes Oecolampadius a German religious reformer from the Electorate of the Palatinate. His real name was Hussgen or Heussgen, a name first changed to Hausschein and then into the Greek equivalent, which is derived from οίκος oikos, "house," and λαμπάς lampas, "lamp"