1541 events in history

Jan 15 King Francis I of France gives Jean-François Roberval a commission to settle the province of New France (Canada) and provide for the spread of the "Holy Catholic faith"
Feb 12 Santiago, Chile is founded by Pedro de Valdivia
Apr 7 Francis Xavier leaves Lisbon on a mission to the Portuguese East Indies
May 8 Hernando de Soto reaches the Mississippi River and names it Río de Espíritu Santo
Jun 26 Francisco Pizarro is assassinated in Lima by the son of his former companion and later antagonist, Diego Almagro the younger. Almagro is later caught and executed
Aug 23 French explorer Jacques Cartier lands near Quebec City in his third voyage to Canada
Aug 29 The Ottoman Turks capture Buda, the capital of the Hungarian Kingdom
Sep 11 Santiago, Chile, is destroyed by indigenous warriors, led by Michimalonco
Sep 13 After three years of exile, John Calvin returns to Geneva to reform the church under a body of doctrine known as Calvinism
Sep 30 Spanish conquistador Hernando de Soto and his forces enter Tula territory in present-day western Arkansas, encountering fierce resistance
Dec 10 Thomas Culpeper and Francis Dereham are executed for having affairs with Catherine Howard, Queen of England and wife of Henry VIII