Died in 1543

Jan 2 Francesco Canova da Milano an Italian lutenist and composer. He was born in Monza, near Milan, and worked for the papal court for almost all of his career. Francesco was heralded throughout Europe as the foremost lute composer of his time. More of his music is preserved than of any other lutenist of the period, and his work continued to influence composers for more than a century after his death
Jan 3 Juan Rodríguez Cabrillo a Portuguese explorer noted for his exploration of the west coast of North America on behalf of Spain. Cabrillo was the first European explorer to navigate the coast of present day California in the United States
Jan 9 Guillaume du Bellay a French diplomat and general under King Francis I.
Jan 29 Nagao Tamekage a retainer of Japanese feudal lord Uesugi Fusayoshi, and a daimyo in his own right, during Japan's Sengoku period. According to some scholars, such as George Bailey Sansom, Nagao Tamekage's career makes him representative of the emergence of the daimyo, and the shift of regional power from the shugo, Governors, and other government officials into independent lords. He is perhaps most famous as the biological father of Nagao Kagetora, who would be adopted into the Uesugi family as Uesugi Kenshin, and would go on to become one of the most famous of all Sengoku period daimyo
Feb 13 Johann Eck a German Scholastic theologian and defender of Catholicism during the Protestant Reformation.
Feb 21 Ahmad ibn Ibrahim al-Ghazi a Somali Imam and General of the Adal Sultanate who invaded Abyssinia and defeated several Abyssinian emperors. With the help of an army mainly composed of Somalis, Imam Ahmad , embarked on a conquest which brought three-quarters of Abyssinia under the power of the Muslim Sultanate of Adal during the Abyssinian-Adal War from 1529-43
Apr 23 Susanna of Bavaria a German noblewoman. Born in Munich, she was the daughter of Albert IV, Duke of Bavaria, and Kunigunde of Austria, herself the daughter of Holy Roman Emperor Frederick III and Eleanor of Portugal. Her paternal grandparents were Albert III, Duke of Bavaria, and Anna of Brunswick-Grubenhagen-Einbeck
May 3 Altobello Melone an Italian painter of the Renaissance.
May 24 Nicolaus Copernicus a Renaissance mathematician and astronomer who formulated a model of the universe that placed the Sun rather than the Earth at its center. The publication of this model in his book De revolutionibus orbium coelestium just before his death in 1543 is considered a major event in the history of science, triggering the Copernican Revolution and making an important contribution to the Scientific Revolution
Jun 19 Mary Boleyn the sister of English queen consort Anne Boleyn and a member of the Boleyn family, which enjoyed considerable influence during the reign of King Henry VIII of England. Some historians claim she was Anne's younger sister, but her children believed Mary was the elder, as do most historians today
Aug 10 Ludwig Senfl a Swiss composer of the Renaissance, active in Germany. He was the most famous pupil of Heinrich Isaac, was music director to the court of Maximilian I, Holy Roman Emperor, and was an influential figure in the development of the Franco-Flemish polyphonic style in Germany
Aug 29 Maria of Jülich-Berg born in Jülich, the daughter of Wilhelm IV, Duke of Jülich-Berg and Sibylle of Brandenburg.
Nov 29 Hans Holbein the Younger a German artist and printmaker who worked in a Northern Renaissance style. He is best known as one of the greatest portraitists of the 16th century. He also produced religious art, satire, and Reformation propaganda, and made a significant contribution to the history of book design. He is called "the Younger" to distinguish him from his father, Hans Holbein the Elder, an accomplished painter of the Late Gothic school
Nov 30 Francesco Granacci an Italian painter of the Renaissance.
Dec 27 George Margrave of Brandenburg-Ansbach a Margrave of Brandenburg-Ansbach from the House of Hohenzollern.
Dec 29 Maria Salviati an Italian noblewoman, the daughter of Lucrezia di Lorenzo de' Medici and Jacopo Salviati. She married Giovanni dalle Bande Nere and was the mother of Cosimo I de Medici. Her husband died 30 November 1526, leaving her a widow at the age of 27. Salviati never remarried; after her husband's death she adopted the somber garb of a novice, which is how she is remembered today as numerous late portraits show her attired in black and white