Died in 1546

Jan 4 Camillo Boccaccino an Italian painter of the Renaissance period, active mainly in Cremona and regions of Lombardy.
Jan 11 Gaudenzio Ferrari a Northern Italian painter and sculptor of the Renaissance.
Jan 13 Jeremias I of Constantinople Ecumenical Patriarch of Constantinople two times, from 1522 to 1524 and from 1525 to 1546.
Jan 18 Blasco Núñez Vela the first Spanish viceroy of Peru, from May 15, 1544 to January 18, 1546. He was charged by King Charles I with the enforcement of the controversial New Laws, which dealt with the failure of the encomienda system to protect the indigenous people of America from the rapacity of the conquistadors and their descendants
Jan 21 Azai Sukemasa built Odani Castle for the Azai clan, including his son Azai Hisamasa, to rule.
Feb 18 Martin Luther a German friar, Catholic priest, professor of theology and seminal figure of the 16th-century movement in Christianity known later as the Protestant Reformation. Initially an Augustinian friar, Luther came to reject several teachings and practices of the Roman Catholic Church. He strongly disputed the claim that freedom from God's punishment for sin could be purchased with money. He confronted indulgence salesman Johann Tetzel, a Dominican friar, with his Ninety-Five Theses in 1517. His refusal to retract all of his writings at the demand of Pope Leo X in 1520 and the Holy Roman Emperor Charles V at the Diet of Worms in 1521 resulted in his excommunication by the Pope and condemnation as an outlaw by the Emperor
Feb 23 Francis Count of Enghien a French prince of the blood. He was the son of Charles de Bourbon, Duke of Vendôme
Mar 1 George Wishart a Scottish religious reformer and Protestant martyr.
Mar 26 Thomas Elyot an English diplomat and scholar.
Mar 31 Alfonso d'Avalos a condottiero of Spanish-Italian origin.
Apr 22 García de Loaysa a Spanish Archbishop of Seville and Cardinal.
May 29 David Beaton Archbishop of St Andrews and the last Scottish Cardinal prior to the Reformation.
Jul 4 Hayreddin Barbarossa an Ottoman admiral of the fleet who was born in the Ottoman island of Midilli and died in Constantinople , the Ottoman capital. Barbarossa's naval victories secured Ottoman dominance over the Mediterranean during the mid 16th century, from the Battle of Preveza in 1538 until the Battle of Lepanto in 1571
Jul 16 Anne Askew an English poet and Protestant who was condemned as a heretic. She is the only woman on record known to have been both tortured in the Tower of London and burnt at the stake. She is also one of the earliest female poets to compose in the English language and the first Englishwoman to demand a divorce
Aug 2 Peter Faber the first Jesuit priest and theologian, who was also a co-founder of the Society of Jesus. Pope Francis announced his canonization on 17 December 2013
Aug 3 Étienne Dolet a French scholar, translator and printer. Dolet was a controversial figure throughout his lifetime. His scientific scholarship aroused many suspicions concerning his religious views. After being imprisoned several times, he was eventually arrested and burned with his books on orders of the theological faculty of the Sorbonne
Aug 3 Antonio da Sangallo the Younger an Italian architect active during the Renaissance.
Sep 3 Peter IV Rareș twice voievod of Moldavia: 20 January 1527 to 18 September 1538 and 19 February 1541 to 3 September 1546. He was an illegitimate child born to Ștefan cel Mare. His mother was Maria Răreșoaia of Hârlău, whose existence is not historically documented but who is said to have been the wife of a wealthy boyar fish-merchant nicknamed Rareș "rare-haired". Rareș thus was not Petru’s actual name but a nickname of his mother’s husband
Nov 1 Giulio Romano an Italian painter and architect. A pupil of Raphael, his stylistic deviations from high Renaissance classicism help define the 16th-century style known as Mannerism. Giulio's drawings have long been treasured by collectors; contemporary prints of them engraved by Marcantonio Raimondi were a significant contribution to the spread of 16th-century Italian style throughout Europe