Born in 1554

Jan 9 Pope Gregory XV Pope from 9 February 1621 to his death in 1623.
Jan 20 Sebastian of Portugal King of Portugal and the Algarves from 11 June 1557 to 4 August 1578 and the penultimate Portuguese monarch of the House of Aviz.
Mar 26 Charles Duke of Mayenne a French nobleman of the house of Guise and a military leader of the Catholic League, which he headed during the French Wars of Religion, following the assassination of his brothers at Blois in 1588. In 1596, when he made peace with Henri of Navarre, the wars were essentially at an end. He was the second son of Francis of Lorraine, Duke of Guise and Anna d'Este, the daughter of Ercole d'Este II, Duke of Ferrara and Renée of France
Mar 28 Tsarevich Ivan Ivanovich of Russia Tsarevich - the heir apparent - of the Tsardom of Russia, being the second son of Ivan the Terrible and Anastasia Romanovna, and elder brother of Feodor.
May 20 Paolo Bellasio an Italian composer and organist of the late Renaissance. He is generally considered to be a member of the Roman School, though unusually for the group he seems to have written only madrigals
May 21 Juan de Saavedra a Spanish conquistador in Peru and Chile, and the discoverer of the site of Valparaíso, Chile.
Jun 3 Pietro de' Medici the youngest son of Cosimo I de' Medici, Grand Duke of Tuscany and Eleonora di Toledo.
Jul 5 Elisabeth of Austria Queen of France Queen of France from 1570 to 1574 as the wife of King Charles A member of the House of Habsburg, she was the daughter of Maximilian II, Holy Roman Emperor, and Maria of Spain.
Oct 3 Fulke Greville 1st Baron Brooke an Elizabethan poet, dramatist, and statesman who sat in the House of Commons at various times between 1581 and 1621, when he was raised to the peerage.
Oct 20 Bálint Balassi a Hungarian Renaissance lyric poet. He wrote mostly in Hungarian, but was also proficient in further eight languages: Latin, Italian, German, Polish, Turkish, Slovak, Croatian and Romanian. He is the founder of modern Hungarian lyric and erotic poetry
Nov 30 Philip Sidney remembered as one of the most prominent figures of the Elizabethan age. His works include Astrophel and Stella, The Defence of Poesy , and The Countess of Pembroke's Arcadia
Dec 17 Ernest of Bavaria Prince-elector-archbishop of the Archbishopric of Cologne from 1583 to 1612 as successor of the expelled Gebhard Truchsess von Waldburg. He was also bishop of Münster, Hildesheim, Freising and Liège
Dec 19 Philip William Prince of Orange the eldest son of William the Silent by his first wife Anna van Egmont. He became Prince of Orange in 1584 and Knight of the Golden Fleece in 1599