Died in 1563

Jan 12 Macarius Metropolitan of Moscow a notable Russian cleric, writer, and icon painter who served as the Metropolitan of Moscow and all Russia from 1542 until 1563.
Feb 2 Hans Neusidler a German composer and lutenist of the Renaissance.
Feb 4 Wilhelm von Brandenburg the Archbishop of Riga from 1539 to 1561.
Feb 24 Francis Duke of Guise a French soldier and politician.
Mar 24 Hosokawa Harumoto a Japanese daimyo of the Muromachi and Sengoku periods, and the head of the Hosokawa clan. Harumoto's childhood name was Sōmei-maru. He was born to Hosokawa Sumimoto, another renowned samurai of the Muromachi era
Mar 28 Heinrich Glarean a Swiss music theorist, poet and humanist. He was born in Mollis and died in Freiburg
May 21 Martynas Mažvydas the author and the editor of the first printed book in the Lithuanian language.
Jun 9 William Paget 1st Baron Paget an English statesman and accountant who held prominent positions in the service of Henry VIII, Edward VI and Mary I.
Jun 24 Yuri of Uglich Prince of Uglich, and the second son of Vasily III of Russia and Elena Glinskaya, as well as being the younger brother of Ivan the Terrible. He was born deaf mute, and was thus never considered to be a candidate as heir to the Russian throne
Jul 22 Francisco de Villagra a Spanish conquistador, and three times governor of Chile.
Aug 11 Bartolomé de Escobedo a Spanish composer of the Renaissance.
Aug 18 Étienne de La Boétie a French judge, writer, and "a founder of modern political philosophy in France." He "has been best remembered as the great and close friend of the eminent essayist Michel de Montaigne, in one of history's most notable friendships.".
Sep 17 Henry Manners 2nd Earl of Rutland an English nobleman. He also held the title of 13th Baron de Ros of Hamlake, a title to which he acceded in 1543
Sep 22 Teodósio I Duke of Braganza the 5th Duke of Braganza, among other titles. He is known for ceding the title of Duke of Guimarães to Infante Duarte of Aviz, alongside some of the wealth and properties of the House of Braganza
Dec 29 Sebastian Castellio a French preacher and theologian; and one of the first Reformed Christian proponents of religious toleration, freedom of conscience and thought.