Died in 1596

Jan 27 Francis Drake an English sea captain, privateer, navigator, slaver, and politician of the Elizabethan era. Drake carried out the second circumnavigation of the world, from 1577 to 1580
Feb 7 George I Landgrave of Hesse-Darmstadt the Landgrave of Hesse-Darmstadt from 1567 to 1596.
Feb 17 Friedrich Sylburg a German classical scholar.
Feb 19 Blaise de Vigenère a French diplomat, cryptographer, translator and alchemist.
Mar 23 Henry Unton an Elizabethan English diplomat.
Apr 3 Koca Sinan Pasha an Ottoman grand vizier, Ottoman military figure, and statesman.
May 6 Giaches de Wert a Franco-Flemish composer of the late Renaissance, active in Italy. Intimately connected with the progressive musical center of Ferrara, he was one of the leaders in developing the style of the late Renaissance madrigal. He was one of the most influential of late sixteenth-century madrigal composers, particularly on Claudio Monteverdi, and his later music was formative on the development of music of the early Baroque era
Jun 21 Jean Liebault a doctor and agronomist, born in Dijon.
Jul 15 Giuseppe Valeriano an Italian painter and architect, priest of the Jesuit order, and active in Rome, Spain, and Naples.
Aug 11 Hamnet Shakespeare the only son of William Shakespeare and Anne Hathaway, and the fraternal twin of Judith Shakespeare. He died at age 11. Some Shakespearean scholars speculate on the relationship between Hamnet and his father's later play Hamlet, as well as on possible connections between Hamnet's death and the writing of King John, Romeo and Juliet, Julius Caesar, and Twelfth Night
Sep 9 Anna Jagiellon queen of Poland from 1575 to 1586. She was the daughter of Poland's King Sigismund I the Old, and the wife of Stephen Báthory. She was elected, along with her then fiancé, Báthory, as co-ruler in the second election of the Polish–Lithuanian Commonwealth. Anna was the last member of the Jagiellon dynasty
Sep 15 Leonhard Rauwolf a German physician, botanist, and traveller. His main notability arises from a trip he made through the Levant and Mesopotamia in 1573-75. The motive of the trip was to search for herbal medicine supplies. Shortly after he returned, he published a set of new botanical descriptions with an herbarium. Later he published a general travel narrative about his visit
Sep 28 Margaret Stanley Countess of Derby the only surviving daughter of Henry Clifford, 2nd Earl of Cumberland and Lady Eleanor Brandon. Her maternal grandparents were Charles Brandon, 1st Duke of Suffolk and Mary Tudor, former queen consort of France. Mary was the third daughter of King Henry VII of England and Elizabeth of York
Oct 3 Florent Chrestien a French satirist and Latin poet.
Nov 1 Pierre Pithou a French lawyer and scholar. He is also known as Petrus Pithoeus
Nov 9 George Peele most noted for his supposed but not universally accepted collaboration with William Shakespeare on the play Titus Andronicus.
Dec 23 Hattori Hanzō a famous samurai and ninja of the Sengoku era, credited with saving the life of Tokugawa Ieyasu and then helping him to become the ruler of united Japan. Today, he is often a subject of varied portrayal in modern popular culture
Dec 30 Manuel de Sá a Portuguese Jesuit theologian and exegete.