Died in 1649

Jan 22 Alessandro Turchi an Italian painter of the early Baroque, born and active mainly in Verona, and moving late in life to Rome. He also went by the name Alessandro Veronese or the nickname L'Orbetto
Jan 30 Charles I of England monarch of the three kingdoms of England, Scotland, and Ireland from 27 March 1625 until his execution in 1649.
Feb 11 Marie of Prussia Margravine of Brandenburg-Bayreuth a Prussian duchess by birth and Margravine of Brandenburg-Bayreuth by marriage.
Mar 9 Arthur Capell 1st Baron Capell of Hadham an English politician who sat in the House of Commons from 1640 until 1641 when he was raised to the peerage as Baron Capell. He supported the Royalist cause in the English Civil War and was executed on the orders of parliament in 1649
Mar 9 James Hamilton 1st Duke of Hamilton a Scottish nobleman and influential political and military leader during the Wars of the Three Kingdoms.
Mar 9 Henry Rich 1st Earl of Holland an English courtier, peer and soldier. A member of the influential Rich family, he was the son of Robert Rich, 1st Earl of Warwick, and his wife, Penelope Devereux, and the younger brother of Robert, 2nd Earl of Warwick
Mar 16 Jean de Brébeuf a French Jesuit missionary who travelled to New France in 1625. There he worked primarily with the Huron for the rest of his life, except for a time back in France from 1629 to 1633. He learned their language and culture
Mar 19 Gerardus Vossius a Dutch classical scholar and theologian.
Mar 26 John Winthrop a wealthy English Puritan lawyer and one of the leading figures in the founding of the Massachusetts Bay Colony, the first major settlement in New England after Plymouth Colony. Winthrop led the first large wave of migrants from England in 1630, and served as governor for 12 of the colony's first 20 years of existence. His writings and vision of the colony as a Puritan "city upon a hill" dominated New England colonial development, influencing the governments and religions of neighboring colonies
Apr 29 Dodo (prince) a Manchu prince and military general of the early Qing Dynasty. His title was "Prince Yu of the First Rank"
May 14 Friedrich Spanheim a Calvinistic theology professor at the University of Leiden.
May 17 Gabriel Lalemant a Jesuit missionary and one of the eight Canadian Martyrs.
Jun 3 Manuel de Faria e Sousa a Portuguese historian and poet, frequently writing in Spanish.
Jun 17 Stanisław Lubomirski (1583–1649) a Polish-Lithuanian nobleman.
Jun 30 Simon Vouet perhaps best remembered for helping to introduce the Italian Baroque style of painting to France.
Jul 20 Padovanino an Italian painter of the late-Mannerist and early-Baroque Venetian school, best known for having mentored Pietro Liberi, Giulio Carpioni, and Bartolommeo Scaligero. He was the son of Dario Varotari the Elder and the brother of Chiara Varotari, who accompanied him on his travels and assisted with his work
Jul 29 David Teniers the Elder born at Antwerp.
Aug 7 Maria Leopoldine of Austria the second spouse of her first cousin, Holy Roman Emperor Ferdinand III. As such, she was empress of the Holy Roman Empire. She died while giving birth to the couple's only child, Archduke Charles Joseph of Austria
Aug 10 Vittoria Farnese d'Este an Italian noblewoman. She was born in Parma, the daughter of Ranuccio I Farnese, Duke of Parma and Margherita Aldobrandini, niece of Pope Clement VIII. On 12 February 1648 she married Francesco I d'Este, widower of her sister Maria Farnese. The couple had one child, Vittoria , and Vittoria died in Modena, giving birth to her. Francesco then married a third time, to Lucrezia Barberini, in Loreto in October 1654
Aug 21 Richard Crashaw an English poet, styled "the divine," and known as one of the central figures associated with the Metaphysical poets in 17th Century English literature. The son of a prominent Puritan minister, Crashaw was educated at Charterhouse School and Pembroke College, Cambridge. After taking a degree, Crashaw began to publish religious poetry and to teach at Cambridge
Aug 27 Catherine of Brandenburg ruler of Transylvania between 1629 and 1630.
Sep 6 Robert Dudley (explorer) an English explorer and cartographer. In 1594, he led an expedition to the West Indies, of which he wrote an account. The illegitimate son of Robert Dudley, 1st Earl of Leicester, he inherited the bulk of the Earl's estate in accordance with his father's will, including Kenilworth Castle. In 1603–1605 he tried unsuccessfully to establish his legitimacy in court. After that he left England forever, finding a new existence in the service of the Grand Dukes of Tuscany. There he worked as an engineer and shipbuilder and designed and published Dell'Arcano del Mare, the first maritime atlas to cover the whole world. He was also a skilled navigator and mathematician. In Italy he styled himself "Earl of Warwick and Leicester", as well as "Duke of Northumberland", a title recognized by the Emperor Ferdinand II
Sep 15 John Floyd (Jesuit) an English Jesuit, known as a controversialist. He is known under the pseudonyms Daniel à Jesu, Hermannus Loemelius, and George White under which he published
Oct 3 Giovanni Diodati a Swiss-born Italian Calvinist theologian and translator. He was the first translator of the Bible into Italian from Hebrew and Greek sources
Oct 6 Tsarevich Dmitry Alexeyevich of Russia the first son and heir of Tsar Alexis of Russia and Maria Miloslavskaya, brother of Tsarevich Alexei Alexeyevich of Russia, Tsar Feodor III of Russia and Tsar Ivan V of Russia and half-brother of Tsar Peter the Great. He died before he had a chance to succeed to the throne. He is buried in the Cathedral of the Archangel
Oct 16 Isaac van Ostade a Dutch genre and landscape painter.
Nov 19 Piotr Zbylitowski a Polish poet. Courtier of Stanisław Górka and Stanisław Czarnkowski. In his satirical dialogues—Rozmowa szlachcica polskiego z cudzoziemcem , Przygana wymyślnym strojom białogłowskim , Schadzka ziemiańska —he often criticizes some customs of the Polish nobility, mainly drunkenness, quietism, luxury and disappearance of knight's spirit. He was a first cousin of Andrzej Zbylitowski
Nov 19 Caspar Schoppe a German controversialist and scholar.
Dec 4 William Drummond of Hawthornden a Scottish poet.
Dec 7 Charles Garnier (missionary) a Jesuit missionary, who was killed in a Tobacco Nation village on December 7, 1649.
Dec 8 Noël Chabanel a Jesuit missionary at Sainte-Marie among the Hurons, and one of the Canadian Martyrs.
Dec 25 Adam Kazanowski a noble of the Polish-Lithuanian Commonwealth from 1633, Greater Crown Stolnik from 1634, Court Chamberlain and castellan of Sandomierz from 1637, Court Marshall from 1643, żupnik of Wieliczka from 1642, starosta barcicki, borysowski, kozienicki, rumieński, solecki, nowotarski, warecki, bielski and a close and influential friend of King Władysław IV Vasa.